Welcome to Biomedicine & Prevention

Biomedicine & Prevention is a peer-reviewed, open access journal that publishes original research articles as well as review articles in several areas of the life sciences. The journal’s Editorial Board covers several subject areas mainly focusing on prevention and health promotion. Prevention is covered not as an exclusive health competence discipline but in a holistic way, including environmental sciences, engineering, physics, legal implications and legislation.

Tuberculosis 2020

Tuberculosis (TB) still causes an out-sized burden of morbidity and mortality, remaining one of the human infections with the highest prevalence worldwide. This is calling for efficient measures of prevention and control, in particular for an efficient preventive vaccine and the rapid identification of subjects with active-TB capable to transmit the bacillus. However, the attempts to study new vaccines have been only partially successful or even completely unsuccessful. Similarly, current diagnostic tests are affected by a large number of limitations due to reduced or suboptimal sensitivity, time to results, or instrumental needs and costs. To identify novel vaccine targets and develop efficient diagnostic tools, research has to focus on the understanding the mutual interaction of the MTB and host studying the different infectioun stages. This approach can bring both to novel vaccine targets and biomarkers for the diagnosis and monitoring vaccine effectiveness.

Nursing Science and Prevention

In the middle of the 1900s, the concept of health changed deeply. In fact, while at the beginning of the last century, health was defined as the “absence of disease”, in 1946 the World Health Organization defined health as “a state of complete physical, mental and social well-being”. Prevention plays a key role in improving well-being because it impedes diseases from affecting people or attempts to reduce the burden of disease.

Up to date on prevention in Occupational Medicine

The main change in Occupational Medicine is probably represented by the progressive transition from the focus on “Prevention of Disease” to the focus on “Promotion of Health”. In the light of the definition of health given by the World Health Organization as a “state of complete physical, mental and social well being, and not merely the absence of disease or infirmity”, and considering that people generally spend at work a large fraction of their lives, there is nowdays large consensus that workplace represents a privileged target for active interventions of health promotion. Smokers, overweigth and sedentary workers are the subgroups in whom most of interventions have been realized until now.

Biomedicine and Prevention: a Public Health perspective

The twentieth century has been characterized by virulent debates about the causal role of environmental vs. genetic determinants of diseases. At times, these diatribes turned more into ideological rather than scientific face-offs. However, today we are more aware that the large majority - if not all - disease processes, as well as human differences, are determined by both genetics and environment.

The Molecular Pathology between Prevention and Care: the New Renaissance of Anatomic Pathology

The history of Anatomic Pathology is a fundamental part of the history of modern medicine. Giovanni Battista Morgagni and Rudolf Virchow, the fathers of modern medicine, were pathologists1. At the present, the Anatomic Pathology is based on multiple activities aimed to patients’ diagnostic care. The classical pathological results was based on ancillary macroscopic and microscopic diagnosis of the diseases, by using traditional methods of morphological investigation in order to identify the relationship between the pathogenic mechanisms and clinical experience – the so-called “evidence-based medicine”.